What Are Clinical Trials?

A clinical trial is a type of research study that finds out if a new medical therapy is safe and effective. Participants of a trial receive specific interventions, such as a new drug or procedure, while researchers monitor the effectiveness of the intervention. These trials contribute to the advancement of medical knowledge and improve care for others.
 

Why Do We Need Clinical Trials?

Clinical trials are an essential part of advancing medical knowledge which benefits everyone who may require these treatments. Before doctors are able to provide new treatments and medications, the safety and effectiveness must be studied. Clinical trials help us understand which therapy works and are safe to provide for a specific disease. 

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Who Can Take Part in Clinical Trials?

Eligibility to join a clinical trial is determined by specific criteria unique to each study. These criteria often include age, gender, type of disease, and overall health. These eligibility criteria help researchers gather accurate data and measure the intervention effects on specific groups. If you are interested in joining a clinical trial, please ask a healthcare provider to help determine if a study is a good fit for you.
 

What Happens in a Clinical Trial?

In a clinical trial, participants receive care from their doctor and a specific intervention, such as a new medication or procedure. Researchers closely monitor participants in how the treatment affects their health and any potential side effects. Clinical trials are organized into four phases to test safety and effectiveness of the new treatment before it becomes widely available:

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• Phase 1: Small group of participants tests the treatment to determine its safety and appropriate dosage.  

• Phase 2: Moderate group of participants test the treatment’s effectiveness and continue to gather more information on safety and side effects.

• Phase 3: The new treatment is compared to the standard of care in a large group of participants to confirm the effectiveness of the therapy. 

• Phase 4: After the treatment is approved and available to the public, researchers continue to monitor effectiveness and safety in the general population.
   

 

Are Clinical Trials Safe?

Clinical trials follow strict safety measures and are closely monitored by regulatory agencies and ethics committees to protect participants. Participants are informed of potential side effects before enrolling and are closely monitored to ensure safety throughout the trial.
 

Why Might Someone Join a Clinical Trial?

Each person may have a different reason to enroll in a clinical trial. Some people may join to try new treatments that show promise in treating their disease. Others may want to advance medical knowledge and help in the process to find new cures. 
 

What Should I Think About Before Joining a Clinical Trial?

Before enrolling in a clinical trial, it’s essential to ask questions to your healthcare provider. Here are some helpful things to ask:

• What is the purpose of this trial?

• What will I have to do if I join?

• How long does the trial last?

• What are the risks and benefits?

• Who will be in charge of my care?